AI-enabled Site-Specific Integration Cell Line Development Platform



Cell line development (CLD) plays a pivotal role in determining the robustness and cost-effectiveness of downstream bioprocessing development. Great Bay Bio developed a proprietary AlfaCell® platform that applies Site-Specific Integration (SSI) technology and AI-enabled cell selection to accurately insert the target genes into specific “hot spot” within the genome of a host cell line. AlfaCell® platform significantly reduces time, effort, and cost that are associated with the development of high-performance mammalian cell lines.


Data and Model Collaboration

Strategic Partnership Models

    AlfaCell® RCB: Construction from DNA to high-yield and stable RCB
    AlfaCell® Out-licensing
    Customized AlfaCell® development: Develop your own cell line into a Site-Specific Integration (SSI) platform
    Transfer of AlfaCell® technology: Transfer of our patented technology